Final Agenda:
Download workshop booklet
Wednesday, September 7
| 12:00 pm | Arrival at Axiogenesis Headquarter / LUNCH |
| 01:05 pm | Felix von Haniel “Welcome/ Overview” |
| 01:25 pm | Dr. Stefan Mann (Cytocentrics / Victor Chang Cardiac Research Institute) “SIDS and modulation of INaL by hypoxia, investigated in iPSC derived cardiomyocytes” |
| 01:50 pm | Dr. Marc Rogers (Metrion) “Validating in vitro cardiac ion channel assays and screening platforms with human iPS cell-derived cardiomyocytes for improved prediction of clinical pro-arrhythmia risk” |
| 02:20 pm | Dr. Benjamin Bader (Neuroproof) “Functional electrophysiological phenotyping of human iPSC-derived neurons grown on MEAs – a novel approach for in vitro disease modeling of neurodegenerative diseases” |
| 02:40 pm | Coffee break |
| 03:30 pm | Live Demonstrations
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| 07:00 pm | Dinner |
Thursday, September 8
| 08:45 am | Arrival at Axiogenesis Headquarter |
| 09:05 am | Dr. Dietmar Hess (Axiogenesis) “Neural news: insights into Axiogenesis’ expanded neural product portfolio“ |
| 09:30 am | Dr. Lia Scarabottolo (Axxam) ”Use of iPSC-derived cells in HTS. Still a dream or reality?” |
| 09:55 am | Dr. Hua Rong Lu (Janssen Pharmacauticals) “Human stem cell research for drug-induced cardiac and neuronal safety / toxicities: Global Safety Pharmacology’s ongoing strategy” |
| 10:20 am | Coffee Break |
| 10:50 am | Dr. Greg Luerman (Axiogenesis) “Case Studies in Cardiac Safety / Toxicity Assessment Using Human iPSC-Derived Cell Systems” |
| 11:15 am | Dr. Richard Printemps (Physiostim) “Human induced pluripotent stem cells derived Cor.4U® ventricular cardiomyocytes (hiPSC-CM) as a predictive tool for preclinical safety assessment” |
| 11:40 am | Dr. Elena Dragicevic (Nanion Technologies) “Electrophysiology in iPSC-derived neurons and cardiomyocytes: Microelectrode Array (MEA), optogenetics and automapted patch clamp approaches” |
| 12:00 pm | Lunch Break |
| 01:00 pm | Heribert Bohlen (Axiogenesis) KEYNOTE: “From vision to reality: ipsc-derived cells in drug development” |
| 01:25 pm | Dr. Paul Walker (Cyprotex) “Confocal high content screening of cardiac microtissues for the improved prediction of drug induced structural cardiotoxicity” |
| 01:50 pm | Dr. Denise Franz (University of Rostock) “Electrophysiological characterization of human induced pluripotent stem cell-derived dopaminergic neurons using manual and automated patch clamp systems ” |
| 02:15 pm | Dr. Ian Hayes (Luxcel Biosciences Ltd.) “Assessing the impact of drug treatment on cardiomyocyte function through combined analysis of beating, metabolic flux and cellular oxygenation” |
| 02:40 pm | Coffee Break |
| 03:30 pm | Live Demonstrations
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| 04:45 pm | Shuttle Bus to Hotel |
Friday, September 9
| 08:45 am | Arrival at Axiogenesis Headquarter |
| 09:05 am | Dr. Vincent Milleret (Ectica Technologies) “iPSC-derived neural cultures in 3DProSeed hydrogel well plates” |
| 09:25 am | Dr. Francesco Pasqualini (Wyss Translational Center, University and ETH Zurich) “Quality assurance systems in cell-based drug discovery and regenerative medicine” |
| 09:50 am | Dr. Stephane Bedut (Servier) “Human iPSC-derived cardiomyocytes voltage and calcium signal recording with the Hamamatsu FDSS for drugs and cell lines characterization“ |
| 10:10 am | Coffee Break |
| 10:40 am | Live Demonstrations |
| 12:00 am | Departure
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Wet Lab Demos:
Cytotox / Mitotox Assay
Multi Electrode Array
Impedance
Optogenetics
HTS Calcium / Voltage Sensitive Dyes
Cardiac Cell Contractile Force Measurement