Cor.At® cardiomyocytes are 100% pure, primary-like cardiomyocytes derived from mouse embryonic stem cells (ES cells). Cor.At® cardiomyocytes are reproducing an authentic cellular environment, which is fully characterized, including electrophyisology, gene analysis, and immunostaining. Due to their unique properties, Cor.At® cardiomyocytes can be used for various applications and experimental set-ups within the pharma industry as well as in academic research.
All common manual patch clamp set-ups as well as automated patch clamp systems (PatchXpress, Patchliner, QPatch) are supported to produce highly valuable and relevant data. Cor.At® cardiomyocytes are also suitable for preclinical assessment of cardiac cytotoxicity and mitochondrial toxicity, and a predictive model for drug profiling and target discovery (e.g. hypertrophy studies, GPCR effects, siRNA, tissue engineering). Cor.At® cardiomyocytes are compatible with all common assay systems and instrumentation, including label-free detection systems.
