$0,44 per pill

Active Ingredient: Imipramine

Dosage: 25mg, 50mg, 75mg

Tofranil: A Brief Overview

Tofranil, also known by its generic name imipramine, is classified as a tricyclic antidepressant (TCA). It acts by restoring the balance of certain natural substances (neurotransmitters) in the brain, which are believed to be imbalanced in people with depression.

Originally approved by the U.S. Food and Drug Administration (FDA) in 1959, Tofranil has been used for the treatment of depression in adults and adolescents. It is also prescribed for the management of bedwetting in children aged 6 years and older.

Imipramine, the active ingredient in Tofranil, works by increasing the levels of serotonin and norepinephrine in the brain. These neurotransmitters play a key role in regulating mood, emotions, and behavior, and their deficiency is associated with depression.

Studies have shown that Tofranil can be effective in alleviating symptoms of depression, including feelings of sadness, hopelessness, and fatigue. It is often prescribed as a second-line treatment for depression when other medications have not been successful.

It is important to note that Tofranil should only be used under the supervision of a healthcare provider, as it can have side effects and may interact with other medications. Patients should follow their doctor’s instructions carefully and report any unusual symptoms or reactions while taking Tofranil.

Understanding Tofranil as an Antidepressant

Tofranil, or imipramine, belongs to the class of tricyclic antidepressants (TCAs), which are commonly used to treat major depressive disorder. It works by increasing the levels of neurotransmitters such as serotonin and norepinephrine in the brain, which helps improve mood and alleviate symptoms of depression.

Many studies have shown the efficacy of Tofranil in managing depression, with research indicating that it can be as effective as newer antidepressant medications. Tofranil is often recommended for individuals who do not respond well to other antidepressants or have treatment-resistant depression.

It is important to note that Tofranil may take several weeks to start showing noticeable improvements in mood, as it needs time to build up in the body and produce its therapeutic effects. Regular monitoring by a healthcare provider is crucial to determine the right dosage and track any potential side effects.

Despite being an older medication, Tofranil continues to be a valuable option for individuals struggling with depression, offering a reliable and well-established treatment approach.


$0,44 per pill

Active Ingredient: Imipramine

Dosage: 25mg, 50mg, 75mg

Understanding Tofranil as a Tricyclic Antidepressant

Tofranil, or imipramine, belongs to the class of tricyclic antidepressants (TCAs), which are one of the first generations of antidepressants developed. TCAs work by increasing the levels of neurotransmitters such as serotonin and norepinephrine in the brain, which helps to improve mood, relieve symptoms of depression, and restore the balance of these chemicals.

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Mechanism of Action of Tofranil

Imipramine functions by inhibiting the reuptake of serotonin and norepinephrine in the brain. This action prolongs the effects of these neurotransmitters in the synaptic gap between neurons, leading to enhanced neurotransmission and improved mood stability.

Indications for Tofranil Use

Tofranil is primarily prescribed for the treatment of major depressive disorder, as well as other mood disorders such as dysthymia (persistent depressive disorder). It is also utilized off-label for conditions like chronic pain, panic disorder, and certain types of eating disorders.

Side Effects of Tofranil

Common side effects of Tofranil may include dry mouth, constipation, blurred vision, dizziness, drowsiness, and weight gain. It is important to monitor for more serious potential side effects like changes in heart rate, seizures, and allergic reactions.

Comparative Efficacy of Tofranil

In clinical studies, Tofranil has demonstrated efficacy in treating depression comparable to other TCAs and newer classes of antidepressants. Each patient may respond differently to treatment, so individualized assessment and monitoring are essential in determining the optimal medication regimen.

Research and Clinical Trials

Clinical trials have assessed the effectiveness and safety of Tofranil in treating depression across different age groups and severity levels. Research studies provide valuable insights into the therapeutic benefits and potential risks associated with using Tofranil as an antidepressant.
For more information on the pharmacology and clinical use of tricyclic antidepressants like Tofranil, you can refer to reputable sources such as the National Institute of Mental Health (NIMH) or the American Psychiatric Association (APA).

Manufacturers and Availability of Generic Tofranil

Tofranil, also known as imipramine, is available in generic form from various manufacturers. Some of the well-known manufacturers of generic Tofranil include:

  1. Teva Pharmaceuticals: Teva Pharmaceuticals is a leading manufacturer of generic medications, including imipramine.
  2. Sandoz: Sandoz is a subsidiary of Novartis and produces a range of generic pharmaceuticals, including Tofranil.
  3. Watson Pharmaceuticals: Watson Pharmaceuticals, now known as Actavis, is another prominent manufacturer of generic imipramine.

Availability of generic Tofranil may vary depending on the region and pharmacy. It is advisable to consult with a healthcare provider or pharmacist to inquire about the availability of generic imipramine in a specific location.

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In recent years, the availability of generic medications, including Tofranil, has increased significantly. This trend has been driven by the expiration of patents on branded drugs, allowing generic manufacturers to produce more affordable versions of the medication.

Studies have shown that generic medications are bioequivalent to their branded counterparts, meaning they have the same active ingredient and produce similar therapeutic effects. According to the US Food and Drug Administration (FDA), generic drugs undergo rigorous testing to ensure they meet safety and efficacy standards.

The Benefits of Purchasing Tofranil from an Online Pharmacy

When considering buying Tofranil, also known as imipramine, for the treatment of depression or other related conditions, utilizing an online pharmacy can offer numerous advantages. Here are some of the key benefits:

  • Convenience: Online pharmacies provide the convenience of ordering medications from the comfort of your home without the need to visit a physical store.
  • Privacy and Confidentiality: Online purchasing of Tofranil allows for discreet transactions, maintaining your privacy and confidentiality.
  • Cost Savings: Online pharmacies often offer competitive prices for medications like Tofranil, providing potential cost savings compared to traditional brick-and-mortar pharmacies.
  • Accessibility: Online pharmacies can make it easier for individuals in remote or rural areas to access medications like Tofranil without the need to travel long distances.
  • Availability of Generic Options: Many online pharmacies offer generic versions of Tofranil, providing more affordable alternatives for those seeking cost-effective treatment options.
  • Delivery to Your Doorstep: Online pharmacies typically offer home delivery services, ensuring that your Tofranil medication is conveniently delivered to your doorstep.

It’s important to ensure that when purchasing Tofranil or any medication online, you choose a reputable and licensed online pharmacy to guarantee the quality and authenticity of the product.

For more information on purchasing Tofranil or other antidepressants, consider consulting trusted healthcare providers or reputable online resources such as the U.S. Food and Drug Administration (FDA) or the Mayo Clinic.


$0,44 per pill

Active Ingredient: Imipramine

Dosage: 25mg, 50mg, 75mg

Top Antidepressants Offered at

When it comes to finding effective antidepressants, offers a range of top-quality options to cater to diverse needs. Below are some of the top antidepressants available on our platform:

1. Tofranil (Imipramine): Tofranil, also known by its generic name imipramine, is a tricyclic antidepressant that is widely used to treat depression, anxiety, and other mood disorders. It works by restoring the balance of neurotransmitters in the brain, ultimately improving symptoms of depression.

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2. Prozac (Fluoxetine): Prozac is a selective serotonin reuptake inhibitor (SSRI) that helps regulate mood by increasing the levels of serotonin in the brain. It is commonly prescribed for depression, anxiety disorders, and certain eating disorders.

3. Zoloft (Sertraline): Zoloft is another popular SSRI that is effective in treating depression, obsessive-compulsive disorder (OCD), panic disorder, and social anxiety disorder. It helps improve mood and reduce anxiety by targeting serotonin levels.

4. Lexapro (Escitalopram): Lexapro is a widely prescribed antidepressant that belongs to the class of drugs known as selective serotonin reuptake inhibitors (SSRIs). It is used to treat depression and generalized anxiety disorder by regulating serotonin levels in the brain.

5. Effexor (Venlafaxine): Effexor is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is effective in treating major depressive disorder and generalized anxiety disorder. It works by increasing the levels of serotonin and norepinephrine in the brain.

At, we prioritize the quality and efficacy of the antidepressants we offer, ensuring that our customers receive safe and reliable medications for their mental health needs.


When it comes to managing depression and other mood disorders, having access to effective medications like Tofranil can make a significant difference in a person’s quality of life. Tricyclic antidepressants like Tofranil have been used for decades to help individuals overcome the challenges of depression. While Tofranil may not be as commonly prescribed today due to the emergence of newer antidepressants with fewer side effects, it still remains a valuable option for individuals who may not respond well to other medications.

It is important to consult with a healthcare professional to determine the best treatment plan for depression, as they can provide guidance on the most suitable medication based on individual needs and medical history. Additionally, exploring online pharmacies like can offer convenience and cost savings when purchasing medications like Tofranil.

As highlighted on, a leading online pharmacy that offers a wide range of antidepressant medications, including Tofranil, individuals can benefit from competitive prices and discreet shipping services. By partnering with reputable manufacturers and ensuring high-quality products, prioritizes customer satisfaction and safety.

In conclusion, while Tofranil may not be the most popular antidepressant on the market today, it continues to play a valuable role in helping individuals manage their mental health. By understanding the benefits of medications like Tofranil and exploring reliable sources for purchasing them, individuals can take proactive steps towards achieving improved well-being and mental wellness.

Category: Anti-Depressants

Tags: Tofranil, Imipramine

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